Positive rectal swabs in young patients recovered from coronavirus disease 2019 (COVID-19)
Identifieur interne : 000280 ( 2020/Analysis ); précédent : 000279; suivant : 000281Positive rectal swabs in young patients recovered from coronavirus disease 2019 (COVID-19)
Auteurs : Bin Zhang [République populaire de Chine] ; Shuyi Liu [République populaire de Chine] ; Yuhao Dong [République populaire de Chine] ; Lu Zhang [République populaire de Chine] ; Qingyang Zhong [République populaire de Chine] ; Yujian Zou [République populaire de Chine] ; Shuixing Zhang [République populaire de Chine]Source :
- The Journal of Infection [ 0163-4453 ] ; 2020.
Abstract
To investigate the widely concerned issue about positive real-time reverse transcription polymerase chain reaction (RT-PCR) test results after discharge in patients recovered from coronavirus disease 2019 (COVID-19).
We identified seven cases of COVID-19 who was readmitted to hospital because of positive RT-PCR after discharge, including three pediatrics and four young adult patients.
Six patients had positive rectal swabs but negative throat swabs, and one patient had positive throat swabs. All the patients continued to be asymptomatic and had unchanged chest computed tomography from previous images. The time from hospital discharge to positive RT-PCR after recovery was 7–11 days. The time from positive to negative rectal swabs was 5-23 days.
The study might suggest the positive RT-PCR after recovery did not mean disease relapse or virus reinfection. Adding RT-PCR test of rectal swabs to the criteria for discharge or discontinuation of quarantine might be necessary.
Url:
DOI: 10.1016/j.jinf.2020.04.023
PubMed: 32335176
PubMed Central: 7177113
Affiliations:
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PMC:7177113Le document en format XML
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<front><div type="abstract" xml:lang="en"><sec><title>Objectives</title>
<p>To investigate the widely concerned issue about positive real-time reverse transcription polymerase chain reaction (RT-PCR) test results after discharge in patients recovered from coronavirus disease 2019 (COVID-19).</p>
</sec>
<sec><title>Methods</title>
<p>We identified seven cases of COVID-19 who was readmitted to hospital because of positive RT-PCR after discharge, including three pediatrics and four young adult patients.</p>
</sec>
<sec><title>Results</title>
<p>Six patients had positive rectal swabs but negative throat swabs, and one patient had positive throat swabs. All the patients continued to be asymptomatic and had unchanged chest computed tomography from previous images. The time from hospital discharge to positive RT-PCR after recovery was 7–11 days. The time from positive to negative rectal swabs was 5-23 days.</p>
</sec>
<sec><title>Conclusion</title>
<p>The study might suggest the positive RT-PCR after recovery did not mean disease relapse or virus reinfection. Adding RT-PCR test of rectal swabs to the criteria for discharge or discontinuation of quarantine might be necessary.</p>
</sec>
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